With a kick off at 7.45pm, and reduced price admission (just £10 for adults), another large crowd is expected at Field Mill for the latest pre-season game.
According to the Sheffield Star, Wednesday will have Chris Adamson set to play again.
There could also be a place at Field Mill for David Graham, who missed the US tour, and an outing for part of the game for Barry Corr, who was due to get matchplay in America but was sidelined by severe food poisoning.
Plans to bring Drew Talbot back into the fold for the friendlies have hit a snag with the striker's knee problem still not cleared up.
Stags boss Peter Shirtliff is looking forward to the challange, and told the Mansfield CHAD, "They are a Championship team and will present us with a similar challege to Derby.
"Wednesday are always a tough team and will provide us with another stern test."